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Fetal antisense oligonucleotide therapy for congenital deafness and vestibular dysfunction
Wang L, Kempton JB, Jiang H, Jodelka FM, Brigande AM, Dumont RA, Rigo F, Lentz JJ, Hastings ML, Brigande JV. Nucleic Acids Res. 2020 Apr 6. PubMed
April 30, 2020
Directed evolution of adenine base editors with increased activity and therapeutic application
Gaudelli NM, Lam DK, Rees HA, Solá-Esteves NM, Barrera LA, Born DA, Edwards A, Gehrke JM, Lee SJ, Liquori AJ, Murray R, Packer MS, Rinaldi C, Slaymaker IM, Yen J, Young LE, Ciaramella G. Nat Biotechnol. 2020 Apr 13. PubMed
Cytosine base editors with minimized unguided DNA and RNA off-target events and high on-target activity
Yu Y, Leete TC, Born DA, Young L, Barrera LA, Lee SJ, Rees HA, Ciaramella G, Gaudelli NM. Nat Commun. 2020 Apr 28;11(1):2052. PubMed
Imaging small molecule-induced endosomal escape of siRNA
Du Rietz H, Hedlund H, Wilhelmson S, Nordenfelt P, Wittrup A. Nat Commun. 2020 Apr 14;11(1):1809. PubMed
Detailed cellular assessment of albumin-bound oligonucleotides: Increased stability and lower non-specific cell uptake
Lacroix A, Fakih HH, Sleiman HF. J Control Release. 2020 Apr 21. PubMed
Page 45 of 212
Page 45 of 212
Fetal antisense oligonucleotide therapy for congenital deafness and vestibular dysfunction
Wang L, Kempton JB, Jiang H, Jodelka FM, Brigande AM, Dumont RA, Rigo F, Lentz JJ, Hastings ML, Brigande JV. Nucleic Acids Res. 2020 Apr 6. PubMed
Directed evolution of adenine base editors with increased activity and therapeutic application
Gaudelli NM, Lam DK, Rees HA, Solá-Esteves NM, Barrera LA, Born DA, Edwards A, Gehrke JM, Lee SJ, Liquori AJ, Murray R, Packer MS, Rinaldi C, Slaymaker IM, Yen J, Young LE, Ciaramella G. Nat Biotechnol. 2020 Apr 13. PubMed
Cytosine base editors with minimized unguided DNA and RNA off-target events and high on-target activity
Yu Y, Leete TC, Born DA, Young L, Barrera LA, Lee SJ, Rees HA, Ciaramella G, Gaudelli NM. Nat Commun. 2020 Apr 28;11(1):2052. PubMed
Imaging small molecule-induced endosomal escape of siRNA
Du Rietz H, Hedlund H, Wilhelmson S, Nordenfelt P, Wittrup A. Nat Commun. 2020 Apr 14;11(1):1809. PubMed
Detailed cellular assessment of albumin-bound oligonucleotides: Increased stability and lower non-specific cell uptake
Lacroix A, Fakih HH, Sleiman HF. J Control Release. 2020 Apr 21. PubMed
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