Archive

Aging-regulated anti-apoptotic long non-coding RNA Sarrah augments recovery from acute myocardial infarction

Trembinski DJ, Bink DI, Theodorou K, Sommer J, Fischer A, van Bergen A, Kuo CC, Costa IG, Schürmann C, Leisegang MS, Brandes RP, Alekseeva T, Brill B, Wietelmann A, Johnson CN, Spring-Connell A, Kaulich M, Werfel S, Engelhardt S, Hirt …

• Long noncoding RNA

April 30, 2020

Radiation-induced extracellular vesicle (EV) release of miR-603 promotes IGF1-mediated stem cell state in glioblastomas

Ramakrishnan V, Xu B, Akers J, Nguyen T, Ma J, Dhawan S, Ning J, Mao Y, Hua W, Kokkoli E, Furnari F, Carter BS, Chen CC. EBioMedicine. 2020 Apr 28;55:102736. PubMed

• Anti-miR/antagomir
• MicroRNA

AntimiR-21 Prevents Myocardial Dysfunction in a Pig Model of Ischemia/Reperfusion Injury

Hinkel R, Ramanujam D, Kaczmarek V, Howe A, Klett K, Beck C, Dueck A, Thum T, Laugwitz KL, Maegdefessel L, Weber C, Kupatt C, Engelhardt S. J Am Coll Cardiol. 2020 Apr 21;75(15):1788-1800. PubMed

• Anti-miR/antagomir
• MicroRNA

Mismatched and wobble base pairs govern primary microRNA processing by human Microprocessor

Li S, Nguyen TD, Nguyen TL, Nguyen TA. Nat Commun. 2020 Apr 21;11(1):1926. PubMed

• Anti-miR/antagomir
• MicroRNA

Delivery of oligonucleotides to bone marrow to modulate ferrochelatase splicing in a mouse model of erythropoietic protoporphyria

Halloy F, Iyer PS, Ćwiek P, Ghidini A, Barman-Aksözen J, Wildner-Verhey van Wijk N, Theocharides APA, Minder EI, Schneider-Yin X, Schümperli D, Hall J. Nucleic Acids Res. 2020 Apr 20. PubMed

• Alternative splicing
• Delivery
• Splice modulation