Page 5 of 194
Small extracellular vesicles containing miR-486-5p promote angiogenesis after myocardial infarction in mice and nonhuman primates
Papers of interest to society members in the field of oligonucleotide therapeutics. Antisense, aptamers, lncRNA, siRNA, splice modulation and ribozymes.
April 23, 2021
Decreased miR-214-3p activates NF-κB pathway and aggravates osteoarthritis progression
Papers of interest to society members in the field of oligonucleotide therapeutics. Antisense, aptamers, lncRNA, siRNA, splice modulation and ribozymes.
January 2021 Paper of the Month
Koblan LW, Erdos MR, Wilson C, Cabral WA, Levy JM, Xiong ZM, Tavarez UL, Davison LM, Gete YG, Mao X, Newby GA, Doherty SP, Narisu N, Sheng Q, Krilow C, Lin CY, Gordon LB, Cao K, Collins FS, Brown JD, Liu DR.
Nature. 2021 Jan;589(7843):608-614.
May 31, 2021
November 2020 Paper of the Month
Building on previous work, here Asami, Nagata, Yoshioka and colleagues from the Tokyo Medical and Dental University and Ionis Pharmaceuticals investigate new heteroduplex oligonucleotide (HDO) designs for antisense oligonucleotides.

March 1, 2021
A Hitchhiker’s Guide to Click-Chemistry with Nucleic Acids
Fantoni NZ, El-Sagheer AH, Brown T. Chem Rev. 2021 Jan 14. Pubmed
February 16, 2021
Page 5 of 194
Page 5 of 194
Small extracellular vesicles containing miR-486-5p promote angiogenesis after myocardial infarction in mice and nonhuman primates
Papers of interest to society members in the field of oligonucleotide therapeutics. Antisense, aptamers, lncRNA, siRNA, splice modulation and ribozymes.
April 23, 2021
Decreased miR-214-3p activates NF-κB pathway and aggravates osteoarthritis progression
Papers of interest to society members in the field of oligonucleotide therapeutics. Antisense, aptamers, lncRNA, siRNA, splice modulation and ribozymes.
January 2021 Paper of the Month
Koblan LW, Erdos MR, Wilson C, Cabral WA, Levy JM, Xiong ZM, Tavarez UL, Davison LM, Gete YG, Mao X, Newby GA, Doherty SP, Narisu N, Sheng Q, Krilow C, Lin CY, Gordon LB, Cao K, Collins FS, Brown JD, Liu DR.
Nature. 2021 Jan;589(7843):608-614.
May 31, 2021
November 2020 Paper of the Month
Building on previous work, here Asami, Nagata, Yoshioka and colleagues from the Tokyo Medical and Dental University and Ionis Pharmaceuticals investigate new heteroduplex oligonucleotide (HDO) designs for antisense oligonucleotides.

March 1, 2021
A Hitchhiker’s Guide to Click-Chemistry with Nucleic Acids
Fantoni NZ, El-Sagheer AH, Brown T. Chem Rev. 2021 Jan 14. Pubmed
February 16, 2021
Page 5 of 194
