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Generation and validation of structurally defined antibody-siRNA conjugates


Nanna AR, Kel’in AV, Theile C, Pierson JM, Voo ZX, Garg A, Nair JK, Maier MA, Fitzgerald K, Rader C. Nucleic Acids Res. 2020 Apr 29 PubMed


Big Is Beautiful: Enhanced saRNA Delivery and Immunogenicity by a Higher Molecular Weight, Bioreducible, Cationic Polymer


Blakney AK, Zhu Y, McKay PF, Bouton CR, Yeow J, Tang J, Hu K, Samnuan K, Grigsby CL, Shattock RJ, Stevens MM. ACS Nano. 2020 Apr 20. PubMed


Cationic Amphiphilic Drugs Boost the Lysosomal Escape of Small Nucleic Acid Therapeutics in a Nanocarrier-Dependent Manner


Van de Vyver T, Bogaert B, De Backer L, Joris F, Guagliardo R, Van Hoeck J, Merckx P, Van Calenbergh S, Ramishetti S, Peer D, Remaut K, De Smedt SC, Raemdonck K. ACS Nano. 2020 Apr 28;14(4):4774-4791. PubMed


Vaccination against non-mutated neoantigens induced in recurrent and future tumors


Garrido G, Schrand B, Levay A, Rabasa Capote A, Ferrantella A, Da Silva DM, D’Eramo F, Marijt KA, Zhang Z, Kwon D, Kortylewski M, Kast WM, Dudeja V, van Hall T, Gilboa E. Cancer Immunol Res. 2020 Apr 15. PubMed


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