BLADE Directed Evolution of SaCas9 gRNAs Improves Gene Editing Efficiency
Date: December 11, 2025Time: 11-12pm EST / 5-6pm CET Title: BLADE Directed Evolution of SaCas9 gRNAs Improves Gene Editing Efficiency Description: CRISPR-Cas9 efficiency is often limited by misfolding between the sgRNA scaffold and spacer regions. Using the BLADE-SELEX directed evolution platform, ...
Trainee Spotlight Series: 2025 Oligo Meeting Poster Winners 1
Date: December 4, 2025 Time: 11-12pm EST / 5-6pm CET Title: Enhancing mRNA Nuclease Resistance via Nucleobase-Mimicking Small Molecule Self-Assembly Description: Nucleic acid therapeutics offer high efficacy and specificity but suffer from instability, requiring ultra-low storage temperatures and degrading rapidly in ...
