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MTL-CEBPA, a small activating RNA therapeutic up-regulating C/EBP-α, in patients with advanced liver cancer: a first-in-human, multi-centre, open-label, phase I trial


Sarker D, Plummer R, Meyer T, Sodergren M, Basu B, Chee CE, Huang KW, Palmer DH, Ma YT, Evans TRJ, Spalding DR, Pai M, Sharma R, Pinato DJ, Spicer J, Hunter S, Kwatra V, Nicholls JP, Collin D, Nutbrown R,

April 30, 2020


Treatment of Hemophilia A Using Factor VIII Messenger RNA Lipid Nanoparticles


Chen CY, Tran DM, Cavedon A, Cai X, Rajendran R, Lyle MJ, Martini PGV, Miao CH. Mol Ther Nucleic Acids. 2020 Apr 7;20:534-544 PubMed


Engineered Circular RNA Sponges Act as miRNA Inhibitors to Attenuate Pressure Overload-Induced Cardiac Hypertrophy


Lavenniah A, Luu TDA, Li YP, Lim TB, Jiang J, Ackers-Johnson M, Foo RS. Mol Ther. 2020 Apr 14. pii: S1525-0016(20)30187-8. PubMed


Genomic Clustering Facilitates Nuclear Processing of Suboptimal Pri-miRNA Loci


Shang R, Baek SC, Kim K, Kim B, Kim VN, Lai EC. Mol Cell. 2020 Apr 16;78(2):303-316.e4. PubMed



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