Flash Synthesis of Spherical Nucleic Acids with Record DNA Density
Papers of interest to society members in the field of oligonucleotide therapeutics. Antisense, aptamers, lncRNA, siRNA, splice modulation and ribozymes.
Super-resolution RNA imaging using a rhodamine-binding aptamer with fast exchange kinetics
Sunbul M, Lackner J, Martin A, Englert D, Hacene B, Grün F, Nienhaus K, Nienhaus GU, Jäschke A. Nat Biotechnol. 2021 Feb 11. Pubmed
MiR-CLIP reveals iso-miR selective regulation in the miR-124 targetome
Wang Y, Soneson C, Malinowska AL, Laski A, Ghosh S, Kanitz A, Gebert LFR, Robinson MD, Hall J. Nucleic Acids Res. 2021 Jan 11;49(1):25-37 Pubmed
A ubiquitin ligase mediates target-directed microRNA decay independently of tailing and trimming
Han J, LaVigne CA, Jones BT, Zhang H, Gillett F, Mendell JT. Science. 2020 Dec 18;370(6523):eabc9546. Pubmed
The ZSWIM8 ubiquitin ligase mediates target-directed microRNA degradation
Shi CY, Kingston ER, Kleaveland B, Lin DH, Stubna MW, Bartel DP. Science. 2020 Dec 18;370(6523):eabc9359. Pubmed
Splicing-associated chromatin signatures: a combinatorial and position-dependent role for histone marks in splicing definition
Agirre E, Oldfield AJ, Bellora N, Segelle A, Luco RF. Nat Commun. 2021 Jan 29;12(1):682. Pubmed
RNA structure-wide discovery of functional interactions with multiplexed RNA motif library
Komatsu KR, Taya T, Matsumoto S, Miyashita E, Kashida S, Saito H. Nat Commun. 2020 Dec 8;11(1):6275. Pubmed
Functional Atlas of Primary miRNA Maturation by the Microprocessor
Rice GM, Shivashankar V, Ma EJ, Baryza JL, Nutiu R. Mol Cell. 2020 Dec 3;80(5):892-902.e4. Pubmed
Design and application of circular RNAs with protein-sponge function
Schreiner S, Didio A, Hung LH, Bindereif A. Nucleic Acids Res. 2020 Nov 24:gkaa1085 Pubmed
Modified aptamers as reagents to characterize recombinant human erythropoietin products
Jankowski W, Lagassé HAD, Chang WC, McGill J, Jankowska KI, Gelinas AD, Janjic N, Sauna ZE. Sci Rep. 2020 Oct 29;10(1):18593. Pubmed
