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CRISPR-engineered T cells in patients with refractory cancer


Stadtmauer EA, Fraietta JA, Davis MM, Cohen AD, Weber KL, Lancaster E, Mangan PA, Kulikovskaya I, Gupta M, Chen F, Tian L, Gonzalez VE, Xu J, Jung IY, Melenhorst JJ, Plesa G, Shea J, Matlawski T, Cervini A, Gaymon AL,

February 29, 2020


Evaluation and minimization of Cas9-independent off-target DNA editing by cytosine base editors


Doman JL, Raguram A, Newby GA, Liu DR. Nat Biotechnol. 2020 Feb 10. PubMed


Confluence of theory and experiment reveals the catalytic mechanism of the Varkud satellite ribozyme


Ganguly A, Weissman BP, Giese TJ, Li NS, Hoshika S, Rao S, Benner SA, Piccirilli JA, York DM. Nat Chem. 2020 Feb;12(2):193-201. PubMed


High-throughput identification of synthetic riboswitches by barcode-free amplicon-sequencing in human cells


Strobel B, Spöring M, Klein H, Blazevic D, Rust W, Sayols S, Hartig JS, Kreuz S. Nat Commun. 2020 Feb 5;11(1):714. PubMed


Impact of Phosphorothioate Chirality on Double-Stranded siRNAs: A Systematic Evaluation of Stereopure siRNA Designs


Sakamuri S, Eltepu L, Liu D, Lam S, Meade BR, Liu B, Dello Iacono G, Kabakibi A, Luukkonen L, Leedom T, Foster M, Bradshaw CW. Chembiochem. 2019 Dec 21. PubMed


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