BLADE Directed Evolution of SaCas9 gRNAs Improves Gene Editing Efficiency
Date: December 11, 2025 Time: 11-12pm EST / 5-6pm CET Title: BLADE Directed Evolution of SaCas9 gRNAs Improves Gene Editing Efficiency Description: CRISPR-Cas9 efficiency is often limited by misfolding between the sgRNA scaffold and spacer regions. Using the BLADE-SELEX directed evolution ...
Trainee Spotlight Series: 2025 Oligo Meeting Poster Winners 1
Date: December 4, 2025 Time: 11-12pm EST / 5-6pm CET Title: Enhancing mRNA Nuclease Resistance via Nucleobase-Mimicking Small Molecule Self-Assembly Description: Nucleic acid therapeutics offer high efficacy and specificity but suffer from instability, requiring ultra-low storage temperatures and degrading rapidly in ...
New Approaches for Functional Oligonucleotides: RNA Activation and Non-Nucleosidic Aptamers.
Date: November 20, 2025 Time: 11-12pm EST / 5-6pm CET Title: New Approaches for Functional Oligonucleotides: RNA Activation and Non-Nucleosidic Aptamers Description: This talk will highlight two complementary approaches aimed at expanding the functional scope of oligonucleotide therapeutics. First, I will ...
DNA-based tools for the study and treatment of Parkinson’s Disease
Date: November 6, 2025 Time: 11-12pm EST / 5-6pm CET Title: DNA-based tools for the study and treatment of Parkinson’s Disease Description: Aptamers are short stretches of DNA that fold into 3-dimensional shapes that can act as pockets for binding other ...
Financing the Future of Individualized Medicine: Funding Models for Rare Genetic Therapies
Date: September 18, 2025 Time: 11-12pm EDT / 5-6pm CEST Title:Financing the Future of Individualized Medicine: Funding Models for Rare Genetic Therapies Description: Individualized medicine has emerged as an approach offering bespoke therapeutics to patients with rare genetic conditions. In spite ...
From Discovery to Deals: The Neurological Oligonucleotide Landscape at a Glance
Date: September 4, 2025 Time: 11-12pm EDT / 5-6pm CEST Title: From Discovery to Deals: The Neurological Oligonucleotide Landscape at a Glance Description: A deep dive on the drug landscape, displaying critical data-driven therapeutic and clinical trial highlights, as well as ...
Strategic IP for Oligonucleotide Therapeutics: Maximizing Innovation Value
Date: August 28, 2025 Time: 11-12pm EDT / 5-6pm CEST Title: Strategic IP for Oligonucleotide Therapeutics: Maximizing Innovation Value Description: This talk will explore the essential elements of an effective IP strategy tailored for oligonucleotide therapeutics, balancing scientific innovation with commercial ...
The importance of involving patients in therapy development; Lessons learned from Duchenne exon skipping
Date: August 21, 2025 Time: 11-12pm EDT / 5-6pm CEST Title: The importance of involving patients in therapy development; Lessons learned from Duchenne exon skipping Description: Duchenne muscular dystrophy is a progressive muscle wasting disease caused by lack of dystrophin protein. ...
Perspectives on Oligonucleotide Therapeutics: A discussion with Rebecca Miles, incoming president of OTS
Date: June 12, 2025 Time: 11-12pm EDT / 5-6pm CEST Title: Perspectives on Oligonucleotide Therapeutics: A discussion with Rebecca Miles, incoming president of OTS Presentation Description: In this interview, Dr. Rebecca Miles, the president-elect of the Oligonucleotide Therapeutics Society, will discuss ...
Trainee Spotlight Series: Poster Winners #OTS24 Session 5
Date: May 15, 2025 Time: 11-12pm EDT / 5-6pm CEST Join us for this Trainee Spotlight webinar featuring trainee Daniel van Leeuwen, poster award winner at the 2024 OTS Annual Meeting. Title: Deciphering the impact of toxic antisense oligonucleotide (ASO) ...
