Trainee Spotlight Series: 2025 Oligo Meeting Poster Winners 3
Date: February 26, 2026 Time: 11am-12pm EST / 5-6pm CET Title: Combinational modulation of DNA Mismatch Repair protein ratios alter CAG repeat instability in hTERT-RPE1 cellular model Description: The somatic expansion of an unstable CAG trinucleotide repeat tract located within the ...
Where Chemistry Meets Purpose
Date: February 12, 2026 Time: 11am-12pm EST / 5-6pm CET Title: Where Chemistry Meets Purpose Description: Sonja will share her journey through academia, industry, pharma, consulting, and now entrepreneurship as she drives Livinovea in the life sciences. What began over 25 ...
Acute CNS Responses to centrally Delivered Oligonucleotides
Date: January 29, 2026 Time: 11am-12pm EST / 5-6pm CET Title: Acute CNS Responses to centrally Delivered Oligonucleotides Description: Oligonucleotides delivered into cerebrospinal fluid elicit two independent, short-lived CNS phenotypes: an immediate neuronal activation phenotype that appears within minutes and resolves ...
Trainee Spotlight Series: 2025 Oligo Meeting Poster Winners 2
Date: January 15, 2026 Time: 11am-12pm EST / 5-6pm CET Title: Sustained muscle function improvement after a single in vivo dose of antibody oligonucleotide conjugate (AOC) in the mdx mouse model for Duchenne muscular dystrophy Description: Duchenne muscular dystrophy results from ...
BLADE Directed Evolution of SaCas9 gRNAs Improves Gene Editing Efficiency
Date: December 11, 2025 Time: 11-12pm EST / 5-6pm CET Title: BLADE Directed Evolution of SaCas9 gRNAs Improves Gene Editing Efficiency Description: CRISPR-Cas9 efficiency is often limited by misfolding between the sgRNA scaffold and spacer regions. Using the BLADE-SELEX directed evolution ...
Trainee Spotlight Series: 2025 Oligo Meeting Poster Winners 1
Date: December 4, 2025 Time: 11-12pm EST / 5-6pm CET Title: Enhancing mRNA Nuclease Resistance via Nucleobase-Mimicking Small Molecule Self-Assembly Description: Nucleic acid therapeutics offer high efficacy and specificity but suffer from instability, requiring ultra-low storage temperatures and degrading rapidly in ...
New Approaches for Functional Oligonucleotides: RNA Activation and Non-Nucleosidic Aptamers.
Date: November 20, 2025 Time: 11-12pm EST / 5-6pm CET Title: New Approaches for Functional Oligonucleotides: RNA Activation and Non-Nucleosidic Aptamers Description: This talk will highlight two complementary approaches aimed at expanding the functional scope of oligonucleotide therapeutics. First, I will ...
DNA-based tools for the study and treatment of Parkinson’s Disease
Date: November 6, 2025 Time: 11-12pm EST / 5-6pm CET Title: DNA-based tools for the study and treatment of Parkinson’s Disease Description: Aptamers are short stretches of DNA that fold into 3-dimensional shapes that can act as pockets for binding other ...
Financing the Future of Individualized Medicine: Funding Models for Rare Genetic Therapies
Date: September 18, 2025 Time: 11-12pm EDT / 5-6pm CEST Title:Financing the Future of Individualized Medicine: Funding Models for Rare Genetic Therapies Description: Individualized medicine has emerged as an approach offering bespoke therapeutics to patients with rare genetic conditions. In spite ...
From Discovery to Deals: The Neurological Oligonucleotide Landscape at a Glance
Date: September 4, 2025 Time: 11-12pm EDT / 5-6pm CEST Title: From Discovery to Deals: The Neurological Oligonucleotide Landscape at a Glance Description: A deep dive on the drug landscape, displaying critical data-driven therapeutic and clinical trial highlights, as well as ...
