Advancing Prime Editing–Based Genome Editing Technologies for Therapeutic Applications
Date: March 26, 2026 Time: 12-1pm EDT / 5-6pm CET Title: Advancing Prime Editing–Based Genome Editing Technologies for Therapeutic Applications Description: In this webinar, I will discuss recent advances in prime editing–based genome engineering, including split prime editing, template-jumping prime editing, ...
Meet the 2026 Trainee Reps
Date: March 19, 2026 Time: 12-1pm EDT / 5-6pm CET Title: A Trainee's Perspective: Advocacy & Research in ALS Description: In this talk, Daniel will introduce himself as one of the two newest trainee representatives on the OTS Board of Directors ...
Trainee Spotlight Series: 2025 Oligo Meeting Poster Winners 4
Date: March 12, 2026 Time: 12-1pm EDT / 5-6pm CET Title: Neonatal Delivery of Exon Skipping Therapeutics Maximizes Brain Dystrophin Rescue in the Mdx52 Mouse Model of DMD Description: In this webinar, I will explore how early-life exon-skipping strategies can be ...
Trainee Spotlight Series: 2025 Oligo Meeting Poster Winners 3
Date: February 26, 2026 Time: 11am-12pm EST / 5-6pm CET Title: Combinational modulation of DNA Mismatch Repair protein ratios alter CAG repeat instability in hTERT-RPE1 cellular model Description: The somatic expansion of an unstable CAG trinucleotide repeat tract located within the ...
Where Chemistry Meets Purpose
Date: February 12, 2026 Time: 11am-12pm EST / 5-6pm CET Title: Where Chemistry Meets Purpose Description: Sonja will share her journey through academia, industry, pharma, consulting, and now entrepreneurship as she drives Livinovea in the life sciences. What began over 25 ...
Acute CNS Responses to centrally Delivered Oligonucleotides
Date: January 29, 2026 Time: 11am-12pm EST / 5-6pm CET Title: Acute CNS Responses to centrally Delivered Oligonucleotides Description: Oligonucleotides delivered into cerebrospinal fluid elicit two independent, short-lived CNS phenotypes: an immediate neuronal activation phenotype that appears within minutes and resolves ...
Trainee Spotlight Series: 2025 Oligo Meeting Poster Winners 2
Date: January 15, 2026 Time: 11am-12pm EST / 5-6pm CET Title: Sustained muscle function improvement after a single in vivo dose of antibody oligonucleotide conjugate (AOC) in the mdx mouse model for Duchenne muscular dystrophy Description: Duchenne muscular dystrophy results from ...
BLADE Directed Evolution of SaCas9 gRNAs Improves Gene Editing Efficiency
Date: December 11, 2025 Time: 11-12pm EST / 5-6pm CET Title: BLADE Directed Evolution of SaCas9 gRNAs Improves Gene Editing Efficiency Description: CRISPR-Cas9 efficiency is often limited by misfolding between the sgRNA scaffold and spacer regions. Using the BLADE-SELEX directed evolution ...
Trainee Spotlight Series: 2025 Oligo Meeting Poster Winners 1
Date: December 4, 2025 Time: 11-12pm EST / 5-6pm CET Title: Enhancing mRNA Nuclease Resistance via Nucleobase-Mimicking Small Molecule Self-Assembly Description: Nucleic acid therapeutics offer high efficacy and specificity but suffer from instability, requiring ultra-low storage temperatures and degrading rapidly in ...
New Approaches for Functional Oligonucleotides: RNA Activation and Non-Nucleosidic Aptamers.
Date: November 20, 2025 Time: 11-12pm EST / 5-6pm CET Title: New Approaches for Functional Oligonucleotides: RNA Activation and Non-Nucleosidic Aptamers Description: This talk will highlight two complementary approaches aimed at expanding the functional scope of oligonucleotide therapeutics. First, I will ...
