Webinars

Date: September 19, 2024 Time: 8am PDT / 11am EDT / 5pm CEST Title: mRNA Nuclear Clustering Leads to a Difference in Mutant Huntingtin mRNA and Protein Silencing by siRNAs In Vivo Description: Huntington’s disease (HD) is an autosomal dominant neurodegenerative disease for which oligonucleotide therapeutics, ...

Date: August 29, 2024 Time: 6am PDT / 9am EDT / 3pm CEST Title: Sequence- and Structure-Dependent Cytotoxicity of Phosphorothioate and 2’-O-Methyl Modified Single-Stranded Oligonucleotides Description: Single-stranded oligonucleotides (SSOs) are a rapidly expanding class of therapeutics. Chemical modifications such as the phosphorothioate (PS) backbone and the ...

Date: July 25, 2024 Time: 8am PDT / 11am EDT / 5pm CEST Title: Nucleic Acid Therapeutics: Successes, Milestones, and Upcoming Innovation Description: Nucleic acid-based therapies have become the third major drug class after small molecules and antibodies. The role of nucleic acid-based therapies has been ...

Date: July 18, 2024 Time: 8am PDT / 11am EDT / 5pm CEST Title: A Nucleic Acid Approach to Antibody Therapeutics Description: Monoclonal antibodies represent a highly successful class of therapeutics that are used to treat complex diseases across a wide range of therapeutic areas. However, ...

Date: July 11, 2024 Time: 8am PDT / 11am EDT / 5pm CEST Title: Application of hydrophobically conjugated siRNAs for the treatment of dermatological and muscular diseases Description: This webinar will focus on siRNA delivery to skin and muscle using hydrophobic conjugates. With a novel delivery ...

Date: August 22, 2024 Time: 8am PDT / 11am EDT / 5pm CEST Title: 2023 OTS Paper of the Year Spotlight: A Framework for Individualized Splice-Switching Oligonucleotide Therapy Description: Splice-switching antisense oligonucleotides (ASOs) could be used to treat a subset of individuals with genetic diseases, but ...