A Direct Comparison of in Vitro and in Vivo Nucleic Acid Delivery Mediated by Hundreds of Nanoparticles Reveals a Weak Correlation
Paunovska K, Sago CD, Monaco CM, Hudson WH, Castro MG, Rudoltz TG, Kalathoor S, Vanover DA, Santangelo PJ, Ahmed R, Bryksin AV, Dahlman JE. Nano Lett. 2018 Mar 5. PubMed
Delivery Pathway Regulation of 3′,3″-Bis-Peptide-siRNA Conjugate via Nanocarrier Architecture Engineering
Sun J, Qiu C, Diao Y, Wei W, Jin H, Zheng Y, Wang J, Zhang L, Yang Z. MolTher Nucleic Acids. 2018 Mar 2;10:75-90. PubMed
Modulation of blood-brain barrier function by a heteroduplex oligonucleotide in vivo
Kuwahara H, Song J, Shimoura T, Yoshida-Tanaka K, Mizuno T, Mochizuki T, Zeniya S, Li F, Nishina K, Nagata T, Ito S, Kusuhara H, Yokota T. Sci Rep. 2018 Mar 12;8(1):4377. PubMed
A Sensitive In Vitro Approach to Assess the Hybridization-Dependent Toxic Potential of High Affinity Gapmer Oligonucleotides
Dieckmann A, Hagedorn PH, Burki Y, Brügmann C, Berrera M, Ebeling M, Singer T, Schuler F. MolTher Nucleic Acids. 2018 Mar 2;10:45-54. PubMed
RNA-Seq Analysis of an Antisense Sequence Optimized for Exon Skipping in Duchenne Patients Reveals No Off-Target Effect
Domenger C, Allais M, François V, Léger A, Lecomte E, Montus M, Servais L, Voit T, Moullier P, Audic Y, Le Guiner C. MolTher Nucleic Acids. 2018 Mar 2;10:277-291. PubMed
Relationship between “LDL-C”, estimated true LDL-C, apolipoprotein B-100, and PCSK9 levels following lipoprotein(a) lowering with an antisense oligonucleotide
Viney NJ, Yeang C, Yang X, Xia S, Witztum JL, Tsimikas S. J ClinLipidol. 2018 Mar 1. pii: S1933-2874(18)30065-5. PubMed
Direct Selection of Fluorescence-Enhancing RNA Aptamers
Gotrik M, Sekhon G, Saurabh S, Nakamoto M, Eisenstein M, Soh HT. J Am Chem Soc. 2018 Mar 14;140(10):3583-3591. PubMed
Prevention of Asthma Exacerbation in a Mouse Model by Simultaneous Inhibition of NF-κB and STAT6 Activation Using a Chimeric Decoy Strategy
Miyake T, Miyake T, Sakaguchi M, Nankai H, Nakazawa T, Morishita R. MolTher Nucleic Acids. 2018 Mar 2;10:159-169. PubMed
Poly-ligand profiling differentiates trastuzumab-treated breast cancer patients according to their outcomes
Domenyuk V, Gatalica Z, Santhanam R, Wei X, Stark A, Kennedy P, Toussaint B, Levenberg S, Wang J, Xiao N, Greil R, Rinnerthaler G, Gampenrieder SP, Heimberger AB, Berry DA, Barker A, Quackenbush J, Marshall JL, Poste G, Vacirca JL, Vidal GA, Schwartzberg LS, Halbert ...
Systematic Discovery of RNA Binding Proteins that Regulate MicroRNA Levels
Nussbacher JK, Yeo GW. Mol Cell. 2018 Mar 15;69(6):1005-1016.e7. PubMed
