Advancing Prime Editing–Based Genome Editing Technologies for Therapeutic Applications
Date: March 26, 2026 Time: 12-1pm EDT / 5-6pm CET Title: Advancing Prime Editing–Based Genome Editing Technologies for Therapeutic Applications Description: In this webinar, I will discuss recent advances in prime editing–based genome engineering, including split prime editing, template-jumping prime editing, ...
Meet the 2026 Trainee Reps
Date: March 19, 2026 Time: 12-1pm EDT / 5-6pm CET Title: A Trainee's Perspective: Advocacy & Research in ALS Description: In this talk, Daniel will introduce himself as one of the two newest trainee representatives on the OTS Board of Directors ...
Trainee Spotlight Series: 2025 Oligo Meeting Poster Winners 4
Date: March 12, 2026 Time: 12-1pm EDT / 5-6pm CET Title: Neonatal Delivery of Exon Skipping Therapeutics Maximizes Brain Dystrophin Rescue in the Mdx52 Mouse Model of DMD Description: In this webinar, I will explore how early-life exon-skipping strategies can be ...
Trainee Spotlight Series: 2025 Oligo Meeting Poster Winners 3
Date: February 26, 2026 Time: 11am-12pm EST / 5-6pm CET Title: Combinational modulation of DNA Mismatch Repair protein ratios alter CAG repeat instability in hTERT-RPE1 cellular model Description: The somatic expansion of an unstable CAG trinucleotide repeat tract located within the ...
Where Chemistry Meets Purpose
Date: February 12, 2026 Time: 11am-12pm EST / 5-6pm CET Title: Where Chemistry Meets Purpose Description: Sonja will share her journey through academia, industry, pharma, consulting, and now entrepreneurship as she drives Livinovea in the life sciences. What began over 25 ...
Acute CNS Responses to centrally Delivered Oligonucleotides
Date: January 29, 2026 Time: 11am-12pm EST / 5-6pm CET Title: Acute CNS Responses to centrally Delivered Oligonucleotides Description: Oligonucleotides delivered into cerebrospinal fluid elicit two independent, short-lived CNS phenotypes: an immediate neuronal activation phenotype that appears within minutes and resolves ...
Trainee Spotlight Series: 2025 Oligo Meeting Poster Winners 2
Date: January 15, 2026 Time: 11am-12pm EST / 5-6pm CET Title: Sustained muscle function improvement after a single in vivo dose of antibody oligonucleotide conjugate (AOC) in the mdx mouse model for Duchenne muscular dystrophy Description: Duchenne muscular dystrophy results from ...
Leveraging Nature’s Carrier: Albumin-Binding Dendritic siRNA for Enhanced Tumor Targeting
Small interfering RNA (siRNA) therapeutics are rapidly reshaping the landscape of precision medicine, offering the ability to silence disease-driving genes with exceptional specificity and durability. However, due to delivery barriers, the promise of siRNA therapy has largely been confined to the liver. Recent advances ...
Newly Approved Drug Shows Clinical and Quality-of-Life Improvements for HAE Patients
Emily Wheeler was 19 when she noticed a gradual swelling in her left foot. Believing it was an allergic reaction, she went to her doctor, who told her it was gout and gave her several pills. An hour later, she started vomiting uncontrollably and ...
BLADE Directed Evolution of SaCas9 gRNAs Improves Gene Editing Efficiency
Date: December 11, 2025 Time: 11-12pm EST / 5-6pm CET Title: BLADE Directed Evolution of SaCas9 gRNAs Improves Gene Editing Efficiency Description: CRISPR-Cas9 efficiency is often limited by misfolding between the sgRNA scaffold and spacer regions. Using the BLADE-SELEX directed evolution ...
