Fluorogenic RNA Mango aptamers for imaging small non-coding RNAs in mammalian cells
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Self-Amplifying RNA Vaccines Give Equivalent Protection against Influenza to mRNA Vaccines but at Much Lower Doses
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A systematic approach to RNA-associated motif discovery
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mRNA Vaccine with Antigen-Specific Checkpoint Blockade Induces an Enhanced Immune Response against Established Melanoma
Wang Y, Zhang L, Xu Z, Miao L, Huang L. Mol Ther. 2018 Feb 7;26(2):420-434. PubMed
Covalent Strategies for Targeting Messenger and Non-Coding RNAs: An Updated Review on siRNA, miRNA and antimiR Conjugates
Grijalvo S, Alagia A, Jorge AF, Eritja R. Genes (Basel). 2018 Feb 6;9(2). pii: E74. PubMed
Mutually exclusive alternative splicing of pre-mRNAs
Jin Y, Dong H, Shi Y, Bian L. Wiley Interdiscip Rev RNA. 2018 Feb 9. PubMed
Splicing regulation by long noncoding RNAs
Romero-Barrios N, Legascue MF, Benhamed M, Ariel F, Crespi M. Nucleic Acids Res. 2018 Feb 7. PubMed
Receptor-Mediated Uptake of Phosphorothioate Antisense Oligonucleotides in Different Cell Types of the Liver
Miller CM, Tanowitz M, Donner AJ, Prakash TP, Swayze EE, Harris EN, Seth PP. Nucleic Acid Ther. 2018 Feb 9. PubMed
DNA aptamer generation by ExSELEX using genetic alphabet expansion with a mini-hairpin DNA stabilization method
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2017 OTS Lifetime Achievement Award Winner Mike Gait, Ph.D
Mike Gait, Ph.D Medical Research Council Michael J. Gait obtained a Ph. D. in 1973 in Chemistry from the University of Birmingham UK. From 1973-75 he was Research Associate at M.I.T with H. Gobind Khorana working one gene synthesis. Since 1975 he has been ...