Chimeric XNA: An Unconventional Design for Orthogonal Informational Systems
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A strongly pairing fifth base: oligonucleotides with a C-nucleoside replacing thymidine
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Structural optimization of pseudorotaxane-forming oligonucleotides for efficient and stable complex formation
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Unlocking P(V): Reagents for chiral phosphorothioate synthesis
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Structural basis for the synergy of 4′- and 2′-modifications on siRNA nuclease resistance, thermal stability and RNAi activity
Harp JM, Guenther DC, Bisbe A, Perkins L, Matsuda S, Bommineni GR, Zlatev I, Foster DJ, Taneja N, Charisse K, Maier MA, Rajeev KG, Manoharan M, Egli M. Nucleic Acids Res. 2018 Aug 11. PubMed
De novo DNA synthesis using polymerase-nucleotide conjugates
Palluk S, Arlow DH, de Rond T, Barthel S, Kang JS, Bector R, Baghdassarian HM, Truong AN, Kim PW, Singh AK, Hillson NJ, Keasling JD. Nat Biotechnol. 2018 Aug;36(7):645-650. PubMed
Application of 2′-O-(2-N-Methylcarbamoylethyl) Nucleotides in RNase H-Dependent Antisense Oligonucleotides
Masaki Y, Iriyama Y, Nakajima H, Kuroda Y, Kanaki T, Furukawa S, Sekine M, Seio K. Nucleic Acid Ther. 2018 Jul 18. PubMed
Adjusting the Structure of 2′-Modified Nucleosides and Oligonucleotides via C4′-α-F or C4′-α-OMe Substitution: Synthesis and Conformational Analysis
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Modification of oligodeoxynucleotides by on-column Suzuki cross-coupling reactions
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Enzymatic synthesis of base-modified RNA by T7 RNA polymerase. A systematic study and comparison of 5-substituted pyrimidine and 7-substituted 7-deazapurine nucleoside triphosphates as substrates
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