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Structure-Guided Engineering of the Homodimeric Mango-IV Fluorescence Turn-on Aptamer Yields an RNA FRET Pair

• Aptamer
• circRNA
• mRNA
• Other papers of interest

May 15, 2020

Safety, Tolerability, and Efficacy of Viltolarsen in Boys with Duchenne Muscular Dystrophy Amenable to Exon 53 Skipping: A Phase 2 Randomized Clinical Trial

• Alternative splicing
• Clinical Development
• Delivery
• Immune Stimulation
• Medicinal Chemistry
• Pre-Clinical Research
• Ribozyme
• Toxicology

Aptamer-T Cell Targeted Therapy for Tumor Treatment Using Sugar Metabolism and Click Chemistry

• Aptamer
• Delivery
• Gene editing

Glycine Enhances Satellite Cell Proliferation, Cell Transplantation, and Oligonucleotide Efficacy in Dystrophic Muscle

• Alternative splicing
• Splice modulation

A Mechanism for microRNA Arm Switching Regulated by Uridylation

Kim H, Kim J, Yu S, Lee YY, Park J, Choi RJ, Yoon SJ, Kang SG, Kim VN. Mol Cell. 2020 May 12:S1097-2765(20)30272-0. Pubmed

• Anti-miR/antagomir
• Long noncoding RNA
• MicroRNA