A Message from Dr. Rebecca Miles
As we begin 2026, I am honored to welcome you to a new year and a new chapter for the Oligonucleotide Therapeutics Society. The start of the year is a natural moment for reflection on how far our field has come, and on the ...
Selection of DNA Aptamers to Inhibit TDP-43 Aggregation in ALS
Date: May 7, 2026 Time: 11-12pm EDT / 5-6pm CEST Register Here Title: Selection of DNA Aptamers to Inhibit TDP-43 Aggregation in ALS Description: Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease characterized by the loss of motor neurons. With an ...
Trainee Spotlight Series: 2025 Oligo Meeting Poster Winners 5
Date: April 16, 2026 Time: 11-12pm EDT / 5-6pm CET Register Here Title: Development of an N=1 Therapeutic Antisense Oligonucleotide for a unique UNC13A variant Description: Rare disorders collectively affect 3 to 10% of the population, but treatment options are scarce. Recently, ...
OTS Member Highlight – Dr. Rebecca Miles
The incoming OTS President, Dr. Rebecca Miles, has always been curious about the way things work, and in high school, a human anatomy and physiology class sparked her passion for researching human diseases. As the first person in her family to pursue higher education, ...
Extended Nucleic Acid Therapeutics: Unlocking potential through tiny methylene chemical modifications
Date: April 2, 2026Time: 11-12pm EDT / 5-6pm CEST Register Here Title: Extended Nucleic Acid Therapeutics: Unlocking potential through tiny methylene chemical modifications Description: Modulation of the backbone structures of oligonucleotides has a profound impact on the pharmacokinetics and pharmacodynamics of RNA medicines. In ...
Small Nuclear RNAs (snRNAs) Enhance RNA Base Editing
Gene editing technologies are transforming molecular medicine, offering unprecedented potential to treat — and even cure — a range of genetic disorders. However, as tools like CRISPR enter clinical settings, concerns about its safety, specificity, and long-term side effects, such as off-target edits or ...
Advancing Prime Editing–Based Genome Editing Technologies for Therapeutic Applications
Date: March 26, 2026 Time: 12-1pm EDT / 5-6pm CET Register Here Title: Advancing Prime Editing–Based Genome Editing Technologies for Therapeutic Applications Description: In this webinar, I will discuss recent advances in prime editing–based genome engineering, including split prime editing, template-jumping prime ...
Trainee Spotlight Series: 2025 Oligo Meeting Poster Winners 4
Date: March 12, 2026 Time: 12-1pm EDT / 5-6pm CET Register Here Title: Neonatal Delivery of Exon Skipping Therapeutics Maximizes Brain Dystrophin Rescue in the Mdx52 Mouse Model of DMD Description: In this webinar, I will explore how early-life exon-skipping strategies can ...
Trainee Spotlight Series: 2025 Oligo Meeting Poster Winners 3
Date: February 26, 2026 Time: 11am-12pm EST / 5-6pm CET Register Here Title: Combinational modulation of DNA Mismatch Repair protein ratios alter CAG repeat instability in hTERT-RPE1 cellular model Description: The somatic expansion of an unstable CAG trinucleotide repeat tract located within ...
Where Chemistry Meets Purpose
Date: February 12, 2026 Time: 11am-12pm EST / 5-6pm CET Register Here Title: Where Chemistry Meets Purpose Description: Sonja will share her journey through academia, industry, pharma, consulting, and now entrepreneurship as she drives Livinovea in the life sciences. What began over ...
