Modulation of Tau Isoforms Imbalance Precludes Tau Pathology and Cognitive Decline in a Mouse Model of Tauopathy
EspÃndola SL, Damianich A, Alvarez RJ, Sartor M, Belforte JE, Ferrario JE, Gallo JM, Avale ME. Cell Rep. 2018 Apr 17;23(3):709-715. PubMed
An Integrated Genome-wide CRISPRa Approach to Functionalize lncRNAs in Drug Resistance
Bester AC, Lee JD, Chavez A, Lee YR, Nachmani D, Vora S, Victor J, Sauvageau M, Monteleone E, Rinn JL, Provero P, Church GM, Clohessy JG, Pandolfi PP. Cell. 2018 Apr 19;173(3):649-664.e20. PubMed
Measuring DNA hybridization using fluorescent DNA-stabilized silver clusters to investigate mismatch effects on therapeutic oligonucleotides
de Bruin D, Bossert N, Aartsma-Rus A, Bouwmeester D. J Nanobiotechnology. 2018 Apr 6;16(1):37. PubMed
RNA-Targeted Therapeutics
Crooke ST, Witztum JL, Bennett CF, Baker BF. Cell Metab. 2018 Apr 3;27(4):714-739. PubMed
Aptamer chemistry
Röthlisberger P, Hollenstein M. Adv Drug Deliv Rev. 2018 Apr 4. PubMed
Alternative-splicing defects in cancer: Splicing regulators and their downstream targets, guiding the way to novel cancer therapeutics
Urbanski LM, Leclair N, Anczuków O. Wiley Interdiscip Rev RNA. 2018 Apr 25:e1476. PubMed
Nucleic acids delivering nucleic acids
Catuogno S, Esposito CL, Condorelli G, de Franciscis V. Adv Drug Deliv Rev. 2018 Apr 6. pii: S0169-409X(18)30058-9 PubMed
Translation of MicroRNA-Based Huntingtin-Lowering Therapies from Preclinical Studies to the Clinic
Miniarikova J, Evers MM, Konstantinova P. Mol Ther. 2018 Apr 4;26(4):947-962. PubMed
Basics of intellectual property and patenting
Presenter: Laurence Gainey, PhD, HGF Intellectual Property Specialists Date: May 24th 2018 Description: This webinar will be a short, basic introduction to the process of patenting as it applies to biotherapeutics, including some territorial differences. It will cover the core requirements for a patent ...
2017 OTS Travel Grant Recipients
Brooke A. Anderson, PhD.,The Scripps Research Institute, Ramanarayanan Krishnamurthy LabAnnabelle Biscans, PhD., UMass Medical School, RNA Therapeutics InstituteMelina Christou, PhD Student, The Cyprus Institute of Neurology and GeneticsAnnika de Jong,MSc,PhD Candidate, Leiden University Medical CenterAlexandre J.Debacker, PhD Student, University of Massachusetts Medical SchoolMahdi Ghavami, MSc, ...
