Silencing of the lncRNA Zeb2-NAT facilitates reprogramming of aged fibroblasts and safeguards stem cell pluripotency
Bernardes de Jesus B, Marinho SP, Barros S, Sousa-Franco A, Alves-Vale C, Carvalho T, Carmo-Fonseca M. Nat Commun. 2018 Jan 8;9(1):94. PubMed
Local and sustained miRNA delivery from an injectable hydrogel promotes cardiomyocyte proliferation and functional regeneration after ischemic injury
Wang LL, Liu Y, Chung JJ, Wang T, Gaffey AC, Lu M, Cavanaugh CA, Zhou S, Kanade R, Atluri P, Morrisey EE, Burdick JA. Nat Biomed Eng. 2017;1:983-992. PubMed
A miRNA181a/NFAT5 axis links impaired T cell tolerance induction with autoimmune type 1 diabetes
Serr I, Scherm MG, Zahm AM, Schug J, Flynn VK, Hippich M, Kälin S, Becker M, Achenbach P, Nikolaev A, Gerlach K, Liebsch N, Loretz B, Lehr CM, Kirchner B, Spornraft M, Haase B, Segars J, Küper C, Palmisano R, Waisman A, Willis RA, Kim ...
The miR-21/PDCD4/AP-1 feedback loop function as a driving force for renal fibrogenesis
Sun Q, Miao J, Luo J, Yuan Q, Cao H, Su W, Zhou Y, Jiang L, Fang L, Dai C, Zen K, Yang J. J Cell Sci. 2018 Jan 19. pii: jcs.202317. PubMed
MicroRNA-149-5p regulates blood-brain barrier permeability after transient middle cerebral artery occlusion in rats by targeting S1PR2 of pericytes
Wan Y, Jin HJ, Zhu YY, Fang Z, Mao L, He Q, Xia YP, Li M, Li Y, Chen X, Hu B. FASEB J. 2018 Jan 18:fj201701121R. PubMed
Design and implementation of a synthetic pre-miR switch for controlling miRNA biogenesis in mammals
Atanasov J, Groher F, Weigand JE, Suess B. Nucleic Acids Res. 2017 Dec 15;45(22):e181. PubMed
Personalized RNA-medicine for pancreatic cancer
Gilles ME, Hao L, Huang L, Rupaimoole R, Lopez-Casas PP, Pulver E, Jeong JC, Muthuswamy SK, Hidalgo M, Bhatia SN, Slack FJ. Clin Cancer Res. 2018 Jan 12. pii: clincanres.2733.2017. PubMed
The aberrant splicing of BAF45d links splicing regulation and transcription in glioblastoma
Aldave G, Gonzalez-Huarriz M, Rubio A, Romero JP, Ravi D, Miñana B, Cuadrado-Tejedor M, García-Osta A, Verhaak R, Xipell E, Martinez-Vélez N, Acanda de la Rocha A, Puigdelloses M, García-Moure M, Marigil M, Gállego Pérez-Larraya J, Marín-Bejar O, Huarte M, Carro MS, Ferrarese R, Belda-Iniesta ...
Partial DNA-guided Cas9 enables genome editing with reduced off-target activity
Yin H, Song CQ, Suresh S, Kwan SY, Wu Q, Walsh S, Ding J, Bogorad RL, Zhu LJ, Wolfe SA, Koteliansky V, Xue W, Langer R, Anderson DG. Nat Chem Biol. 2018 Jan 29. PubMed
Genome-wide Mapping of Off-Target Events in Single-Stranded Oligodeoxynucleotide-Mediated Gene Repair Experiments
Radecke S, Schwarz K, Radecke F. Mol Ther. 2018 Jan 3;26(1):115-131. PubMed
