DROSHA Knockout Leads to Enhancement of Viral Titers for Vectors Encoding miRNA-Adapted shRNAs
Park HH, Triboulet R, Bentler M, Guda S, Du P, Xu H, Gregory RI, Brendel C, Williams DA. Mol Ther Nucleic Acids. 2018 Sep 7;12:591-599. PubMed
Selection of Metastatic Breast Cancer Cell-Specific Aptamers for the Capture of CTCs with a Metastatic Phenotype by Cell-SELEX
Li WM, Zhou LL, Zheng M, Fang J. Mol Ther Nucleic Acids. 2018 Sep 7;12:707-717. PubMed
The sequence features that define efficient and specific hAGO2-dependent miRNA silencing guides
Yan Y, Acevedo M, Mignacca L, Desjardins P, Scott N, Imane R, Quenneville J, Robitaille J, Feghaly A, Gagnon E, Ferbeyre G, Major F. Nucleic Acids Res. 2018 Sep 19;46(16):8181-8196. PubMed
mRNA circularization by METTL3-eIF3h enhances translation and promotes oncogenesis
Choe J, Lin S, Zhang W, Liu Q, Wang L, Ramirez-Moya J, Du P, Kim W, Tang S, Sliz P, Santisteban P, George RE, Richards WG, Wong KK, Locker N, Slack FJ, Gregory RI. Nature. 2018 Sep;561(7724):556-560. PubMed
SELEX methods on the road to protein targeting with nucleic acid aptamers
Bayat P, Nosrati R, Alibolandi M, Rafatpanah H, Abnous K, Khedri M, Ramezani M. Biochimie. 2018 Sep 5;154:132-155. PubMed
Aptamers as Diagnostic Tools in Cancer
Ruiz Ciancio D, Vargas MR, Thiel WH, Bruno MA, Giangrande PH, Mestre MB. Pharmaceuticals (Basel). 2018 Sep 11;11(3). PubMed
Precision Medicine through Antisense Oligonucleotide-Mediated Exon Skipping
Li D, Mastaglia FL, Fletcher S, Wilton SD. Trends Pharmacol Sci. 2018 Sep 30. pii: S0165-6147(18)30145-7. PubMed
The Three S’s for Aptamer-Mediated Control of DNA Nanostructure Dynamics: Shape, Self-Complementarity, and Spatial Flexibility
Shiu SC, Kinghorn AB, Sakai Y, Cheung YW, Heddle JG, Tanner JA. Chembiochem. 2018 Sep 17;19(18):1900-1906. PubMed
Antisense oligonucleotides correct the familial dysautonomia splicing defect in IKBKAP transgenic mice
Sinha R, Kim YJ, Nomakuchi T, Sahashi K, Hua Y, Rigo F, Bennett CF, Krainer AR. Nucleic Acids Res. 2018 Jun 1;46(10):4833-4844. The three joint first authors: Rahul Sinha Young Jin Kim Tomoki Nomakuchi Currently, the most successful oligonucleotide ...
2018 Paper of the Year Award Winner: Alejandra Gonzalez-Duarte, MD
Dr. Alejandra Gonzalez-Duarte, MDNational Institute of Medical Sciences and Nutrition–Salvador Zubiran, MexicoTalk Title: Patisiran, an RNAi Therapeutic, for Hereditary Transthyretin AmyloidosisA.Gonzalez‑Duarte1, D. Adams2, W.D. O’Riordan3, C.-C. Yang4, M. Ueda5, A.V. Kristen6, I. Tournev7, H.H. Schmidt8, T. Coelho9, J.L. Berk10, K.-P. Lin11, G. Vita12, S. Attarian13, ...
