Pervasive Regulatory Functions of mRNA Structure Revealed by High-Resolution SHAPE Probing
Mustoe AM, Busan S, Rice GM, Hajdin CE, Peterson BK, Ruda VM, Kubica N, Nutiu R, Baryza JL, Weeks KM. Cell. 2018 Mar 22;173(1):181-195.e18. PubMed
TargetedmRNATherapy for Ornithine Transcarbamylase Deficiency
Prieve MG, Harvie P, Monahan SD, Roy D, Li AG, Blevins TL, Paschal AE, Waldheim M, Bell EC, Galperin A, Ella-Menye JR, Houston ME. MolTher. 2018 Mar 7;26(3):801-813. PubMed
Innate Immune Response and Off-Target Mis-splicing Are Common Morpholino-Induced Side Effects in Xenopus
Gentsch GE, Spruce T, Monteiro RS, Owens NDL, Martin SR, Smith JC. Dev Cell. 2018 Mar 12;44(5):597-610.e10. PubMed
Non-coding RNAs as therapeutic targets for preventing myocardial ischemia-reperfusion injury
Ong SB, Katwadi K, Kwek XY, Ismail NI, Chinda K, Ong SG, Hausenloy DJ. Expert OpinTher Targets. 2018 Mar;22(3):247-261. PubMed
MetazoanMicroRNAs
Bartel DP. Cell. 2018 Mar 22;173(1):20-51. PubMed
Anti-miRNAoligonucleotides: A comprehensiveguide for design
Lima JF, Cerqueira L, Figueiredo C, Oliveira C, Azevedo NF. RNA Biol. 2018 Mar 23:1-15. PubMed
Functional 5′ UTR mRNA structures in eukaryotic translation regulation and how to find them
Leppek K, Das R, Barna M. Nat Rev Mol Cell Biol. 2018 Mar;19(3):158-174. PubMed
2018 Dr. Alan M. Gewirtz Memorial Scholarship Winner: Justine N. deGruyter & Kyle Knouse
Justine N. deGruyter NSF Graduate Research Fellow Baran Laboratory, The Scripps Research Institute Biography: Justine deGruyter is a New Mexico native and received her B. S. in Chemistry from New Mexico State University, where she graduated with highest honors in 2014. Shortly thereafter, Justine ...
Nusinersen versus Sham Control in Infantile-Onset Spinal Muscular Atrophy
Finkel RS, Mercuri E, Darras BT, Connolly AM, Kuntz NL, Kirschner J, Chiriboga CA, Saito K, Servais L, Tizzano E, Topaloglu H, Tulinius M, Montes J, Glanzman AM, Bishop K, Zhong ZJ, Gheuens S, Bennett CF, Schneider E, Farwell W, De Vivo DC; ENDEAR Study ...
Interview with Robert Habib, MBA
In 2013 I was seeking to run a business that could have an impact in healthcare. John Rossi, Pål Sætrom and Nagy Habib had put together the initial features
