Amplified Self-Immolative Release of Small Molecules by Spatial Isolation of Reactive Groups on DNA-Minimal Architectures
Prinzen AL, Saliba D, Hennecker C, Trinh T, Mittermaier A, Sleiman HF. Angew Chem Int Ed Engl. 2020 Apr 11. Pubmed
Structural disruption of exonic stem-loops immediately upstream of the intron regulates mammalian splicing
Saha K, England W, Fernandez MM, Biswas T, Spitale RC, Ghosh G. Nucleic Acids Res. 2020 May 13:gkaa358. Pubmed
Structure-Guided Engineering of the Homodimeric Mango-IV Fluorescence Turn-on Aptamer Yields an RNA FRET Pair
Trachman RJ 3rd, Cojocaru R, Wu D, Piszczek G, Ryckelynck M, Unrau PJ, Ferré-D'Amaré AR. Structure. 2020 May 1:S0969-2126(20)30126-X. Pubmed
Safety, Tolerability, and Efficacy of Viltolarsen in Boys with Duchenne Muscular Dystrophy Amenable to Exon 53 Skipping: A Phase 2 Randomized Clinical Trial
Clemens PR, Rao VK, Connolly AM, Harper AD, Mah JK, Smith EC, McDonald CM, Zaidman CM, Morgenroth LP, Osaki H, Satou Y, Yamashita T, Hoffman EP; CINRG DNHS Investigators. JAMA Neurol. 2020 May 26 Pubmed
Aptamer-T Cell Targeted Therapy for Tumor Treatment Using Sugar Metabolism and Click Chemistry
Liu CG, Wang Y, Liu P, Yao QL, Zhou YY, Li CF, Zhao Q, Liu GH, Zhang XL. ACS Chem Biol. 2020 May 28. Pubmed
Glycine Enhances Satellite Cell Proliferation, Cell Transplantation, and Oligonucleotide Efficacy in Dystrophic Muscle
Lin C, Han G, Ning H, Song J, Ran N, Yi X, Seow Y, Yin H. Mol Ther. 2020 May 6;28(5):1339-1358. Pubmed
A Mechanism for microRNA Arm Switching Regulated by Uridylation
Kim H, Kim J, Yu S, Lee YY, Park J, Choi RJ, Yoon SJ, Kang SG, Kim VN. Mol Cell. 2020 May 12:S1097-2765(20)30272-0. Pubmed
Base-pair conformational switch modulates miR-34a targeting of Sirt1 mRNA
Baronti L, Guzzetti I, Ebrahimi P, Friebe Sandoz S, Steiner E, Schlagnitweit J, Fromm B, Silva L, Fontana C, Chen AA, Petzold K. Nature. 2020 May 27. Pubmed
Development of an RNAi therapeutic for alpha-1-antitrypsin liver disease
Wooddell CI, Blomenkamp K, Peterson RM, Subbotin VM, Schwabe C, Hamilton J, Chu Q, Christianson DR, Hegge JO, Kolbe J, Hamilton HL, Branca-Afrazi MF, Given BD, Lewis DL, Gane E, Kanner SB, Teckman JH. JCI Insight. 2020 May 7:135348. Pubmed
Selective Naked-Eye Detection of SARS-CoV-2 Mediated by N Gene Targeted Antisense Oligonucleotide Capped Plasmonic Nanoparticles
Moitra P, Alafeef M, Dighe K, Frieman M, Pan D. ACS Nano. 2020 May 28:acsnano.0c03822. Pubmed
