Mutually exclusive alternative splicing of pre-mRNAs
Jin Y, Dong H, Shi Y, Bian L. Wiley Interdiscip Rev RNA. 2018 Feb 9. PubMed
Splicing regulation by long noncoding RNAs
Romero-Barrios N, Legascue MF, Benhamed M, Ariel F, Crespi M. Nucleic Acids Res. 2018 Feb 7. PubMed
Receptor-Mediated Uptake of Phosphorothioate Antisense Oligonucleotides in Different Cell Types of the Liver
Miller CM, Tanowitz M, Donner AJ, Prakash TP, Swayze EE, Harris EN, Seth PP. Nucleic Acid Ther. 2018 Feb 9. PubMed
DNA aptamer generation by ExSELEX using genetic alphabet expansion with a mini-hairpin DNA stabilization method
Hirao I, Kimoto M, Lee KH. Biochimie. 2018 Feb;145:15-21. PubMed
2017 OTS Lifetime Achievement Award Winner Mike Gait, Ph.D
Mike Gait, Ph.D Medical Research Council Michael J. Gait obtained a Ph. D. in 1973 in Chemistry from the University of Birmingham UK. From 1973-75 he was Research Associate at M.I.T with H. Gobind Khorana working one gene synthesis. Since 1975 he has been ...
OTS Launches Webinar Series
OTS is pleased to announce a new webinar series for 2018, bringing you hot topics in the field while giving participants a chance to interact with subject matter experts.
PMP22 antisense oligonucleotides reverse Charcot-Marie-Tooth disease type 1A features in rodent models
Zhao HT, Damle S, Ikeda-Lee K, Kuntz S, Li J, Mohan A, Kim A, Hung G, Scheideler MA, Scherer SS, Svaren J, Swayze EE, Kordasiewicz HB. J Clin Invest. 2018 Jan 2;128(1):359-368. PubMed
(Pro)renin Receptor Inhibition Reprograms Hepatic Lipid Metabolism and Protects Mice from Diet-Induced Obesity and Hepatosteatosis
Ren L, Sun Y, Lu H, Ye D, Han L, Wang N, Daugherty A, Li F, Wang M, Su F, Tao W, Sun J, Zelcer N, Mullick AE, Danser AJ, Jiang Y, He Y, Ruan X, Lu X. Circ Res. 2018 Jan 4. PubMed
Platelet-localized FXI promotes a vascular coagulation-inflammatory circuit in arterial hypertension
Kossmann S, Lagrange J, Jäckel S, Jurk K, Ehlken M, Schönfelder T, Weihert Y, Knorr M, Brandt M, Xia N, Li H, Daiber A, Oelze M, Reinhardt C, Lackner K, Gruber A, Monia B, Karbach SH, Walter U, Ruggeri ZM, Renné T, Ruf W, Münzel ...
Antisense suppression of the nonsense mediated decay factor Upf3b as a potential treatment for diseases caused by nonsense mutations
Huang L, Low A, Damle SS, Keenan MM, Kuntz S, Murray SF, Monia BP, Guo S. Genome Biol. 2018 Jan 15;19(1):4. PubMed
