The Journey of C. Frank Bennett: Caring and Curiosity Drive the Development of Antisense Therapies
The chief scientific officer of Ionis Pharmaceuticals, Dr. C. Frank Bennett, is not someone who comes to work just to do science, but to help his patients. Although he started with little knowledge of antisense drugs when he joined the company more than thirty ...
RSV: Developing Vaccines to Protect the Vulnerable
It’s the middle of winter and, at some point during this season, many people will experience a constellation of symptoms that may include coughing, a sore throat, runny nose, headache, body aches, fevers, and fatigue. Most adults would assume they have a cold or ...
Interview with Shipra Malik, PhD
Shipra Malik, PhDRaman Bahal LabDepartment of Pharmaceutical SciencesUniversity of Connecticut How did you become interested in the field of oligonucleotides? Being from pharmaceutics background, my master’s research was focused on designing nano-formulations to improve the local delivery of small molecules. As I was looking for ...
Inclisiran’s Interesting Path to Treating LDL Cholesterol
When The Medicines Company licensed inclisiran, they envisioned a drug for the masses that would save the healthcare system money and be reasonably priced for patients. Despite the company having little experience in the oligonucleotide therapeutics field, it went all in on the drug, selling ...
Alnylam’s 20-Year Journey of Discovery
Twenty years ago, a group of scientists intent on developing a new class of medicine using RNAi technology came together and formed Alnylam Pharmaceuticals, a name symbolizing their passion for discovery. The bright center star of Orion's belt, Alnilam, has long been used as a ...
Trainee Spotlight Series: Remko Goossens & Priyanka Shukla
Time: 8AM Pacific | 11AM Eastern | 5PM CET Date: May 18, 2023 Speakers: Remko Goossens Leiden University Medical Center Remko will outline our findings concerning the relationship between the splicing speed of ...
Realizing the Promise of CRISPR Therapeutics: In Vivo and Cell Therapy Applications
Time: 8am Pacific | 11am Eastern | 5pm CET Date: May 11, 2023 Laura will be discussing preclinical and clinical data for CRISPR based investigational drug candidates from Intellia Therapeutics. Speakers: Laura Sepp-Lorenzino, ...
The World of GalNAc-Conjugates in Nucleic Acid Therapeutics
Time: 5pm Amsterdam - 9 AM MST Date: April 27, 2023 Speakers: Mano Manoharan, PhD View Bio
Trainee Spotlight Series: Jeremy Hall and Tracy Mallette
Time: 5pm Amsterdam Date: April 13, 2023 Topics/Speakers: Oligo-PROTAC strategy for cell-selective and targeted degradation of activated STAT3 Jeremy Hall City of Hope & Keck Graduate Institute Jeremy will present a summary of the ...
Trainee Spotlight Series: OTS 2022 poster winners
Time: 05:00 PM - Amsterdam, Berlin, Rome, Stockholm, Vienna Date: March 30, 2023 Topics/Speakers: Therapeutic application of engineered U1 snRNAs in retinopathies and other disorders Paolo Pigini Assessing efficacy ...
