President’s Pick – March 2023
The journal RNA, the official publication of the RNA society, has always been one of my favorite journals. RNA’s April issue is devoted to Perspective articles related to nucleic acids therapeutics. Michelle Hastings and Adrian Krainer deserve our thanks as they took on the task ...
10 Years of CRISPR – Developing a Previously Unimaginable Idea to Benefit the World
CRISPR is now a common term, one that you see even in mainstream media. Yet it is incredible to think that its potential for editing genes was published just ten years ago. In a mere decade, the groundbreaking discovery has been successfully developed to ...
The Journey of C. Frank Bennett: Caring and Curiosity Drive the Development of Antisense Therapies
The chief scientific officer of Ionis Pharmaceuticals, Dr. C. Frank Bennett, is not someone who comes to work just to do science, but to help his patients. Although he started with little knowledge of antisense drugs when he joined the company more than thirty ...
RSV: Developing Vaccines to Protect the Vulnerable
It’s the middle of winter and, at some point during this season, many people will experience a constellation of symptoms that may include coughing, a sore throat, runny nose, headache, body aches, fevers, and fatigue. Most adults would assume they have a cold or ...
Interview with Shipra Malik, PhD
Shipra Malik, PhDRaman Bahal LabDepartment of Pharmaceutical SciencesUniversity of Connecticut How did you become interested in the field of oligonucleotides? Being from pharmaceutics background, my master’s research was focused on designing nano-formulations to improve the local delivery of small molecules. As I was looking for ...
Inclisiran’s Interesting Path to Treating LDL Cholesterol
When The Medicines Company licensed inclisiran, they envisioned a drug for the masses that would save the healthcare system money and be reasonably priced for patients. Despite the company having little experience in the oligonucleotide therapeutics field, it went all in on the drug, selling ...
Alnylam’s 20-Year Journey of Discovery
Twenty years ago, a group of scientists intent on developing a new class of medicine using RNAi technology came together and formed Alnylam Pharmaceuticals, a name symbolizing their passion for discovery. The bright center star of Orion's belt, Alnilam, has long been used as a ...
Trainee Spotlight Series: Remko Goossens & Priyanka Shukla
Time: 8AM Pacific | 11AM Eastern | 5PM CET Date: May 18, 2023 Speakers: Remko Goossens Leiden University Medical Center Remko will outline our findings concerning the relationship between the splicing speed of ...
Realizing the Promise of CRISPR Therapeutics: In Vivo and Cell Therapy Applications
Time: 8am Pacific | 11am Eastern | 5pm CET Date: May 11, 2023 Laura will be discussing preclinical and clinical data for CRISPR based investigational drug candidates from Intellia Therapeutics. Speakers: Laura Sepp-Lorenzino, ...
The World of GalNAc-Conjugates in Nucleic Acid Therapeutics
Time: 5pm Amsterdam - 9 AM MST Date: April 27, 2023 Speakers: Mano Manoharan, PhD View Bio










