Glycine Enhances Satellite Cell Proliferation, Cell Transplantation, and Oligonucleotide Efficacy in Dystrophic Muscle
Lin C, Han G, Ning H, Song J, Ran N, Yi X, Seow Y, Yin H. Mol Ther. 2020 May 6;28(5):1339-1358. Pubmed
A Mechanism for microRNA Arm Switching Regulated by Uridylation
Kim H, Kim J, Yu S, Lee YY, Park J, Choi RJ, Yoon SJ, Kang SG, Kim VN. Mol Cell. 2020 May 12:S1097-2765(20)30272-0. Pubmed
Base-pair conformational switch modulates miR-34a targeting of Sirt1 mRNA
Baronti L, Guzzetti I, Ebrahimi P, Friebe Sandoz S, Steiner E, Schlagnitweit J, Fromm B, Silva L, Fontana C, Chen AA, Petzold K. Nature. 2020 May 27. Pubmed
Development of an RNAi therapeutic for alpha-1-antitrypsin liver disease
Wooddell CI, Blomenkamp K, Peterson RM, Subbotin VM, Schwabe C, Hamilton J, Chu Q, Christianson DR, Hegge JO, Kolbe J, Hamilton HL, Branca-Afrazi MF, Given BD, Lewis DL, Gane E, Kanner SB, Teckman JH. JCI Insight. 2020 May 7:135348. Pubmed
Selective Naked-Eye Detection of SARS-CoV-2 Mediated by N Gene Targeted Antisense Oligonucleotide Capped Plasmonic Nanoparticles
Moitra P, Alafeef M, Dighe K, Frieman M, Pan D. ACS Nano. 2020 May 28:acsnano.0c03822. Pubmed
Oligonucleotide Therapeutics: New Drugs That Could Stop COVID-19
In response to the COVID-19 pandemic, scientists around the world have joined together in applying their skills and technologies to fight this global threat. Some of the most promising technologies to fight the coronavirus are based on a new type of drug called oligonucleotide ...
Aging-regulated anti-apoptotic long non-coding RNA Sarrah augments recovery from acute myocardial infarction
Trembinski DJ, Bink DI, Theodorou K, Sommer J, Fischer A, van Bergen A, Kuo CC, Costa IG, Schürmann C, Leisegang MS, Brandes RP, Alekseeva T, Brill B, Wietelmann A, Johnson CN, Spring-Connell A, Kaulich M, Werfel S, Engelhardt S, Hirt MN, Yorgan K, Eschenhagen T, ...
Radiation-induced extracellular vesicle (EV) release of miR-603 promotes IGF1-mediated stem cell state in glioblastomas
Ramakrishnan V, Xu B, Akers J, Nguyen T, Ma J, Dhawan S, Ning J, Mao Y, Hua W, Kokkoli E, Furnari F, Carter BS, Chen CC. EBioMedicine. 2020 Apr 28;55:102736. PubMed
AntimiR-21 Prevents Myocardial Dysfunction in a Pig Model of Ischemia/Reperfusion Injury
Hinkel R, Ramanujam D, Kaczmarek V, Howe A, Klett K, Beck C, Dueck A, Thum T, Laugwitz KL, Maegdefessel L, Weber C, Kupatt C, Engelhardt S. J Am Coll Cardiol. 2020 Apr 21;75(15):1788-1800. PubMed
Mismatched and wobble base pairs govern primary microRNA processing by human Microprocessor
Li S, Nguyen TD, Nguyen TL, Nguyen TA. Nat Commun. 2020 Apr 21;11(1):1926. PubMed
