CDR132L improves systolic and diastolic function in a large animal model of chronic heart failure
Batkai S, Genschel C, Viereck J, Rump S, Bär C, Borchert T, Traxler D, Riesenhuber M, Spannbauer A, Lukovic D, Zlabinger K, Hašimbegović E, Winkler J, Garamvölgyi R, Neitzel S, Gyöngyösi M, Thum T. Eur Heart J. 2020 Oct 22:ehaa791. Pubmed
A MicroRNA Linking Human Positive Selection and Metabolic Disorders
Wang L, Sinnott-Armstrong N, Wagschal A, Wark AR, Camporez JP, Perry RJ, Ji F, Sohn Y, Oh J, Wu S, Chery J, Moud BN, Saadat A, Dankel SN, Mellgren G, Tallapragada DSP, Strobel SM, Lee MJ, Tewhey R, Sabeti PC, Schaefer A, Petri A, Kauppinen ...
The lncRNA H19 alleviates muscular dystrophy by stabilizing dystrophin
[dt_gap height="60"] The lncRNA H19 alleviates muscular dystrophy by stabilizing dystrophin. ……......... [dt_gap height="20"] Zhang Y, Li Y, Hu Q, Xi Y, Xing Z, Zhang Z, Huang L, Wu J, Liang K, Nguyen TK, Egranov SD, Sun C, Zhao Z, Hawke DH, Li J, Sun ...
Human Argonaute2 and Argonaute3 are catalytically activated by different lengths of guide RNA
Park MS, Sim G, Kehling AC, Nakanishi K. Proc Natl Acad Sci U S A. 2020 Oct 29:202015026 Pubmed
RIPK1 gene variants associate with obesity in humans and can be therapeutically silenced to reduce obesity in mice
Karunakaran D, Turner AW, Duchez AC, Soubeyrand S, Rasheed A, Smyth D, Cook DP, Nikpay M, Kandiah JW, Pan C, Geoffrion M, Lee R, Boytard L, Wyatt H, Nguyen MA, Lau P, Laakso M, Ramkhelawon B, Alvarez M, Pietiläinen KH, Pajukanta P, Vanderhyden BC, Liu ...
September 2020 Paper of the Month
Non-alcoholic steatohepatitis (NASH) is caused by accumulation of fat in the liver which can result in liver inflammation, cirrhosis and subsequent liver failure.
Crosstalk between RNA m6A Modification and Non-coding RNA Contributes to Cancer Growth and Progression
Dai F, Wu Y, Lu Y, An C, Zheng X, Dai L, Guo Y, Zhang L, Li H, Xu W, Gao W. Mol Ther Nucleic Acids. 2020 Aug 8;22:62-71. Pubmed
Spatial expression analyses of the putative oncogene ciRS-7 in cancer reshape the microRNA sponge theory
Kristensen LS, Ebbesen KK, Sokol M, Jakobsen T, Korsgaard U, Eriksen AC, Hansen TB, Kjems J, Hager H. Nat Commun. 2020 Sep 11;11(1):4551. Pubmed
Targeting Mitochondria-Located circRNA SCAR Alleviates NASH via Reducing mROS Output
Zhao Q, Liu J, Deng H, Ma R, Liao JY, Liang H, Hu J, Li J, Guo Z, Cai J, Xu X, Gao Z, Su S. Cell. 2020 Oct 1;183(1):76-93.e22. Pubmed
Safety and Immunogenicity of SARS-CoV-2 mRNA-1273 Vaccine in Older Adults
Anderson EJ, Rouphael NG, Widge AT, Jackson LA, Roberts PC, Makhene M, Chappell JD, Denison MR, Stevens LJ, Pruijssers AJ, McDermott AB, Flach B, Lin BC, Doria-Rose NA, O'Dell S, Schmidt SD, Corbett KS, Swanson PA 2nd, Padilla M, Neuzil KM, Bennett H, Leav B, ...
