The First FDA Approval for a GalNAc-conjugated ASO
It starts with a pins-and-needle sensation in your feet, or maybe your gastrointestinal tract has become easily irritated, or you've started to lose weight or develop heart problems. Hereditary ATTR amyloidosis can present differently among patients and with symptoms found in far more common ...
Base Editing in Clinical Trials to Treat Acute Lymphoblastic Leukemia
Base editing has experienced a rapid rise in use since it first came on the scene in 2016, with multiple trials underway, testing its ability to treat conditions with precise, single-letter changes to DNA. The technique presents a potentially more accurate and safer method ...
Interview with Roberto El-Khoury, PhD
Roberto El-Khoury, PhD Eli Lilly and Company How did you become interested in the field? I recall being drawn to the field of oligonucleotide therapeutics in high school biology classes, but it was only years later, when I was offered the opportunity to pursue my ...
2023 Annual Meeting Poster Awardee Spotlight
Time: 8AM PST | 11AM EST | 5PM CET Date: January 25, 2024 Title: siRNA therapy for ex vivo treatment of stem cell grafts and/or donor lymphocytes Description: Allogeneic T cells represent the most potent treatment for hematopoietic malignancies such es ...
President’s Pick Article – December 2023
The OTS Annual Meeting 2023 in Barcelona was a showcase of excellent science and a demonstration of how far our field has advanced over the past nineteen years. Congratulations to our LAA winners Dr. Sudhir Agrawal and Dr. Cy Stein, our other award winners, our ...
2023 Paper of the Year Award – Basic Research Category Winner Sonia Vallabh
Sonia Vallabh The Vallabh/Minikel Lab, The Broad Institute A single-cell map of antisense oligonucleotide activity in the brain https://pubmed.ncbi.nlm.nih.gov/36824749/
2023 Mary Ann Liebert Publishers, Inc. Young Investigator Award Winner Bahal Raman, PhD
Bahal Raman, PhD University of Connecticut
2023 Dr. Alan M. Gewirtz Memorial Scholarship – For Graduate Students Winner Krystal Johnson, PhD
Krystal Johnson, PhD UT Southwestern Medical Center Biography: Krystal joined David Corey’s Lab at UT Southwestern Medical Center (UTSW) to pursue her Ph.D. in 2018 after finishing her B.S. in Biochemistry at UT Austin. She was awarded a NIGMS F31 Diversity Fellowship for her ...
2023 Dr. Alan M. Gewirtz Memorial Scholarship – Postdoctoral Fellows and Junior Industrial Professionals Winner Dan O’Reilly, PhD
Ronald Buijsen, PhD Leiden University Medical Center Biography: Dr. Buijsen has expertise in antisense oligonucleotide (AON) design and optimization in cell models and animal models using a wide variety of molecular, immunohistochemical and
